Spermidine: The secret weapon behind fasting

Spermidine: The secret weapon behind fasting

A new study in Autophagy has the longevity community abuzz about spermidine’s potential to extend healthspan and even lifespan. A longevity star is born, and we’ve got front-row seats!

First things first – let’s address the elephant in the room. Yes, spermidine’s name might raise an eyebrow or two. But don’t let that put you off! This cellular superstar was first isolated from, well, “little swimmers.” But it’s found in all sorts of foods, from aged cheese to whole grains. So, let’s move past the name and focus on the game-changing science! 

Breaking news: Spermidine – not just a mimic, but a must-have!

Exciting new research published in Autophagy has revealed that spermidine isn’t just imitating the benefits of fasting – it’s essential for them! Here’s the scoop.

#1. Fasting’s secret weapon.

Scientists found that when we fast or restrict calories, our bodies ramp up spermidine production. This happens in everything from yeast to flies, mice, and even us humans!

#2.The rapamycin connection.

Remember rapamycin, that famous anti-aging drug? Turns out, its autophagy-boosting and anti-aging effects are tied to increasing spermidine production. Talk about a dynamic duo!

#3. No spermidine, no gain.

When researchers blocked spermidine production, the benefits of fasting – like enhanced cellular cleanup (autophagy) and increased lifespan – disappeared in various organisms.

#4. The ultimate teammate.

This research shows that spermidine isn’t just copying the effects of calorie restriction – it’s an essential player in making those effects happen!

Why this matters to you

This groundbreaking study reveals that spermidine is more than just a “caloric restriction mimetic” – it’s a key player in the anti-aging effects of both fasting and rapamycin. It’s like discovering that the understudy is actually the star of the show!
By understanding spermidine’s crucial role, we’re opening new doors in the world of healthy aging. It’s not just about living longer; it’s about living better, with cells that stay cleaner and more efficient thanks to enhanced autophagy.

Embracing the spermidine lifestyle

So, how can you get more of this cellular superhero in your life? 

  • Enjoy some aged cheese (finally, a health-based reason to eat more cheese!)
  • Incorporate whole grains into your diet
  • Snack on some nuts and seeds

 And, we’ve got Puremidine™ (a pure, highly-concentrated form of spermidine) in HOP Box – it’s gluten-free (unlike many spermidine products) and ready to help you jumpstart your cellular health and longevity.  

Continued learning

Interested in learning more about spermidine?

Here are a few key studies to check out…

Spermidine for rapamycin-induced autophagy and longevity

Spermidine delays aging in humans

Spermidine as an autophagy inducer in humans

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